Urgencia y mecanismo de biosíntesis de metabolitos secundarios microbianos marinos
Keywords:
autoinductor, microorganismo marino, quorum-sensing, metabolito secundario, simbiótico
Abstract
El microorganismo marino es uno de los recursos potenciales biológicamente activos de metabolitos secundarios. Su potencia es tan prometedora que el conocimiento de cómo se produjo su metabolito secundario debe estudiarse y recopilarse. Esos conocimientos permitirán seguir estudiando la mejora de la producción de metabolitos secundarios en el laboratorio. En la naturaleza, la síntesis de metabolitos secundarios ocurre cuando hay un efecto de factores bióticos y abióticos, como el agua de mar y la simbiosis de microbios con otros materiales vivos. Cuando esto se explica en las vías metabólicas, la síntesis de metabolitos secundarios se ve afectada por los nutrientes disponibles y regulada por moléculas autoinductoras a través del mecanismo de detección de quórum.
References
1. Amstrong, E. ,Yan, L., Boud, K.G., Wright, P.C, & Burgess, J.G. 2001. The symbiotic role of marine microbes on living surfaces. Hydrobiologia 461:37-40.
2. Barry, K.J. & Wainwright, N.R. 1997. Biosynthetic induction of a secondary metabolites by a marine bacterum under nutritional stress: potential role of the incomplete oxidation of an organic acid. Bioll Bull 193:274-275.
3. Bibb, M.J. 2005. Regulation of secondary metabolism in streptomycetes. Curr Opin Microbiol 8: 208-215.
4. Bruhn, J.B., Nielsen, K.F., Hjelm, M., Hansen, M., Bresciani, J., Schulz, S. & Gram, L. 2005. Ecology, inhibitory activity, and morphogenesis of a marine antagonistic bacterium belonging to the roseobacter clade. Appl Microbiol Environ 71: 7263-7270.
5. Burgess, J.G. Jordan, E.M. Bregu, M. Mearns-Spragg, A. & Boyd, K.G. 1999. Microbial antagonism: a neglected avenue of natural product research. J Biotechnol 70:27-32.
6. Chakraburtty, R. & Bibb, M.J. 1997. The ppGpp Synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation. J Bacteriol 179: 5854-5861.
7. Chelossi, E., Milanese, M., Milano, A., Pronzato, R. & Riccardi, G. 2004, Characterisation and antimicrobial activity of epibiotic bacteria from Petrosia ficiformis (porifera, demosponsiae). J Exp Mar Biol Ecol 309: 21-33.
8. Claire, A.S. Rittschof, D. Gerhart, D.J. Hooper, I.R. & Bonaventura, J. 1999. Anti-settlement and narcotic action of analogues of diterpene marine natural product antifoulant from octocarals. Mar Biotechnol 1: 427-436.
9. El-Sayed, A.K., Hothersall, J. & Thomas, C.M. 2001. Quorum-sensing-dependent regulation of biosynthesis of the polyketide antibiotic mupirocin in Pseudomonas fluorescens NCIMB 10586. Microbiol 147: 2127-2139.
10. Gonzalez, J.E & Marketon, M.M. 2003. Quorum sensing in Nitrogen-Fixing Rhizobia. Microbiol Mol Biol Rev 67: 574-592.
11. Gudbjarnason, S. 1999. Bioactive Marine Natural Product. Rit Fiskideilar 16:107-110.
12. Gutterson, N. Ziegle, J.S., Warren, G.W. & Layton, T.J. 1988. Genetic determinants for catabolite induction of antibiotic biosynthesis in Pseudomonas fluorescens HV37a. J Bacteriol 170: 380-385.
13. Horinouchi, S., & Beppu, T. 1992. Autoregulatory factors and communication in actinomycetes. Annu Rev Microbiol 46: 377-398.
14. Kokare, C.R., Mahadik, K.R., Kadam, S.S. & Chopade, B.S.
15. 2004. Isolation, characterization and antimicrobial activity of marine halophilic Actinopolyspora species AH1 from the west coast of India. Curr Sci 86:593-597.
16. Long, R.A. & Azam, F. 2001. Antagonistic Interactions among marine pelagic bacteria. Appl Environ Microbiol 67: 4975-4983.
17. Martin, J.F. 2004. Phosphate control of the biosynthesis of antibiotics and other secondary metabolites is mediated by the PhoR-PhoP System: an Unfinished Story. J. Bacteriol
18. (16): 5197-5201.
19. Muller, W.E.G., Schroder, H.J. & Wiens, M. 2004. Approaches for a sustainable exploitation of biodiversity (secondary metabolites ans biomaterials from sponses) in traditional and modern biomedical prospecting:part ii-the benefits. eCAM 1:133-144.
20. Okami, Y. 1982. Potential use of marine microorganisms for antibiotics and enzyme production. Pure & Appl Chem 54:1951-1962.
21. Prochnow, A.M., Evans, F., Saludes, D.D., Stelzer, S., Egan, S., James, S., Webb, J.S. & Kjelleberg, S. 2004. Biofilm development and cell death in the marine bacterium Pseudoalteromonas tunicate. Appl Environ Microbiol 70: 3232-3238.
22. Schroder, H.C., Ushijima, H., Krasko, A., Gamulin, V., Shutze, J. & Muller, I.M. 2003. Emergence and disappearance of an immun molecule, an antimicrobial lectin, in basal metazoa: the achylectin family. J Biol Chem 278: 32810-32817.
23. Shiba, T. & Taga, N. 1980. Heterotrophic bacteria attached to seaweeds. Journal of Experimental Marine Biology and Ecology. 47:251-258.
24. Tabarez, M.R. 2005. Discovery of the new antimicrobial compound 7-o- malonyl macrolactin a. Dissertation Van Der Gemeinsamen Naturwissenschaftlichen Fakultat. Jerman: Universitat Carolo-Wilhelmina.
25. Thakur, N.L., Hensschel, U., Krasko, A., Anil, A.C. & Muller, W.E.G. 2003. Antibcterial activity of the sponse suberites domuncula and its primmorphs: potential basis for chemical defense. Aquatic Microbiol Ecol 31: 77-83.
26. Wiens, M., Luckas, B., Brummer, F., Ammar, M.S.A., Steffen, R. & Batel, R. 2003. Okadaic acid: a potential defense molecule for the sponse Suberites domuncula. Mar Biol 142: 213-223.
27. Yan, L., Boyd, K.G. & Burgess, J.G. 2002. Surface attachment induced production of antimicrobial compounds by marine epiphytic bacteria using modified roller bottle cultivation. Mar Biotecnol 4: 356-366.
28. Yan, L., Boyd, K.G., Adams, D.R. & Burgess, J.G. 2003. Biofilm-specific cross species induction of antimicrobial compounds in bacilli. Appl Environ Microbiol 69: 3719-3727.
29. Zheng, L., Chen, H., Han, X., Lin, W. & Yan, X. 2005. Antimicrobial screening and active compound isolation from marine bacterium NJ6-3-1 associated with the sponse Hymeniacidon perleve. World journal of Microbiology & Biotechnology 21:201-206.
2. Barry, K.J. & Wainwright, N.R. 1997. Biosynthetic induction of a secondary metabolites by a marine bacterum under nutritional stress: potential role of the incomplete oxidation of an organic acid. Bioll Bull 193:274-275.
3. Bibb, M.J. 2005. Regulation of secondary metabolism in streptomycetes. Curr Opin Microbiol 8: 208-215.
4. Bruhn, J.B., Nielsen, K.F., Hjelm, M., Hansen, M., Bresciani, J., Schulz, S. & Gram, L. 2005. Ecology, inhibitory activity, and morphogenesis of a marine antagonistic bacterium belonging to the roseobacter clade. Appl Microbiol Environ 71: 7263-7270.
5. Burgess, J.G. Jordan, E.M. Bregu, M. Mearns-Spragg, A. & Boyd, K.G. 1999. Microbial antagonism: a neglected avenue of natural product research. J Biotechnol 70:27-32.
6. Chakraburtty, R. & Bibb, M.J. 1997. The ppGpp Synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation. J Bacteriol 179: 5854-5861.
7. Chelossi, E., Milanese, M., Milano, A., Pronzato, R. & Riccardi, G. 2004, Characterisation and antimicrobial activity of epibiotic bacteria from Petrosia ficiformis (porifera, demosponsiae). J Exp Mar Biol Ecol 309: 21-33.
8. Claire, A.S. Rittschof, D. Gerhart, D.J. Hooper, I.R. & Bonaventura, J. 1999. Anti-settlement and narcotic action of analogues of diterpene marine natural product antifoulant from octocarals. Mar Biotechnol 1: 427-436.
9. El-Sayed, A.K., Hothersall, J. & Thomas, C.M. 2001. Quorum-sensing-dependent regulation of biosynthesis of the polyketide antibiotic mupirocin in Pseudomonas fluorescens NCIMB 10586. Microbiol 147: 2127-2139.
10. Gonzalez, J.E & Marketon, M.M. 2003. Quorum sensing in Nitrogen-Fixing Rhizobia. Microbiol Mol Biol Rev 67: 574-592.
11. Gudbjarnason, S. 1999. Bioactive Marine Natural Product. Rit Fiskideilar 16:107-110.
12. Gutterson, N. Ziegle, J.S., Warren, G.W. & Layton, T.J. 1988. Genetic determinants for catabolite induction of antibiotic biosynthesis in Pseudomonas fluorescens HV37a. J Bacteriol 170: 380-385.
13. Horinouchi, S., & Beppu, T. 1992. Autoregulatory factors and communication in actinomycetes. Annu Rev Microbiol 46: 377-398.
14. Kokare, C.R., Mahadik, K.R., Kadam, S.S. & Chopade, B.S.
15. 2004. Isolation, characterization and antimicrobial activity of marine halophilic Actinopolyspora species AH1 from the west coast of India. Curr Sci 86:593-597.
16. Long, R.A. & Azam, F. 2001. Antagonistic Interactions among marine pelagic bacteria. Appl Environ Microbiol 67: 4975-4983.
17. Martin, J.F. 2004. Phosphate control of the biosynthesis of antibiotics and other secondary metabolites is mediated by the PhoR-PhoP System: an Unfinished Story. J. Bacteriol
18. (16): 5197-5201.
19. Muller, W.E.G., Schroder, H.J. & Wiens, M. 2004. Approaches for a sustainable exploitation of biodiversity (secondary metabolites ans biomaterials from sponses) in traditional and modern biomedical prospecting:part ii-the benefits. eCAM 1:133-144.
20. Okami, Y. 1982. Potential use of marine microorganisms for antibiotics and enzyme production. Pure & Appl Chem 54:1951-1962.
21. Prochnow, A.M., Evans, F., Saludes, D.D., Stelzer, S., Egan, S., James, S., Webb, J.S. & Kjelleberg, S. 2004. Biofilm development and cell death in the marine bacterium Pseudoalteromonas tunicate. Appl Environ Microbiol 70: 3232-3238.
22. Schroder, H.C., Ushijima, H., Krasko, A., Gamulin, V., Shutze, J. & Muller, I.M. 2003. Emergence and disappearance of an immun molecule, an antimicrobial lectin, in basal metazoa: the achylectin family. J Biol Chem 278: 32810-32817.
23. Shiba, T. & Taga, N. 1980. Heterotrophic bacteria attached to seaweeds. Journal of Experimental Marine Biology and Ecology. 47:251-258.
24. Tabarez, M.R. 2005. Discovery of the new antimicrobial compound 7-o- malonyl macrolactin a. Dissertation Van Der Gemeinsamen Naturwissenschaftlichen Fakultat. Jerman: Universitat Carolo-Wilhelmina.
25. Thakur, N.L., Hensschel, U., Krasko, A., Anil, A.C. & Muller, W.E.G. 2003. Antibcterial activity of the sponse suberites domuncula and its primmorphs: potential basis for chemical defense. Aquatic Microbiol Ecol 31: 77-83.
26. Wiens, M., Luckas, B., Brummer, F., Ammar, M.S.A., Steffen, R. & Batel, R. 2003. Okadaic acid: a potential defense molecule for the sponse Suberites domuncula. Mar Biol 142: 213-223.
27. Yan, L., Boyd, K.G. & Burgess, J.G. 2002. Surface attachment induced production of antimicrobial compounds by marine epiphytic bacteria using modified roller bottle cultivation. Mar Biotecnol 4: 356-366.
28. Yan, L., Boyd, K.G., Adams, D.R. & Burgess, J.G. 2003. Biofilm-specific cross species induction of antimicrobial compounds in bacilli. Appl Environ Microbiol 69: 3719-3727.
29. Zheng, L., Chen, H., Han, X., Lin, W. & Yan, X. 2005. Antimicrobial screening and active compound isolation from marine bacterium NJ6-3-1 associated with the sponse Hymeniacidon perleve. World journal of Microbiology & Biotechnology 21:201-206.
Published
2022-05-23
How to Cite
Kindly Shmuel. (2022). Urgencia y mecanismo de biosíntesis de metabolitos secundarios microbianos marinos. International Journal of Science and Society, 4(2), 138-147. https://doi.org/10.54783/ijsoc.v4i2.457
Section
Articles
Copyright (c) 2022 International Journal of Science and Society
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The copyright in this website and the material on this website (including without limitation the text, computer code, artwork, photographs, images, music, audio material, video material and audio-visual material on this website) is owned by IJSOC and its licensors.
IJSOC grants to you a worldwide non-exclusive royalty-free revocable license to:
- view this website and the material on this website on a computer or mobile device via a web browser;
- copy and store this website and the material on this website in your web browser cache memory; and
- print pages from this website for your use.
- All articles published by Academic Journals are licensed under the Creative Commons Attribution 4.0 International License. This permits anyone to copy, redistribute, remix, transmit and adapt the work provided the original work and source is appropriately cited.
IJSOC does not grant you any other rights in relation to this website or the material on this website. In other words, all other rights are reserved.
For the avoidance of doubt, you must not adapt, edit, change, transform, publish, republish, distribute, redistribute, broadcast, rebroadcast or show or play in public this website or the material on this website (in any form or media) without appropriately and conspicuously citing the original work and source or ACADEMIC JOURNALS prior written permission.
You may request permission to use the copyright materials on this website by writing to compliance@ijsoc.goacademica.com.
IJSOC takes the protection of its copyright very seriously.
If IJSOC discovers that you have used its copyright materials in contravention of the license above, IJSOC may bring legal proceedings against you seeking monetary damages and an injunction to stop you using those materials. You could also be ordered to pay legal costs.
If you become aware of any use of IJSOC' copyright materials that contravenes or may contravene the license above, please report this by email to Compliance@ijsoc.goacademica.com.
If you become aware of any material on the website that you believe infringes your or any other person's copyright, please report this by email to Compliance@ijsoc.goacademica.com.
.png)
.jpg)
.png)
.png)
.png)
.png)
1.png)
.jpg)
-modified.png)
-modified.png)
-modified.png)
