Compounds 7-Hydroxy-6-Metoxic Cytotoxic Cytotoxic Stem Leather From Chisochetonmacrophyllus (Meliaceae) Bark

  • Mellisa Rodrigo Centre of Organic Chemistry study of Manila, Philippines
Keywords: Meliaceae, Chisocheton macrophyllus, pheyepropanoid, coumarin, scopoletin.

Abstract

A phenyl propanoid compound, 7-hydroxy-6-methoxycoumarin has been isolated from the bark of Chisocheton macrophyllus (Meliaceae). The chemical structure of isolated compound was identified on the basis of spectroscopic data including UV, IR, 1D-NMR, 2D-NMR and mass along with comparison with those spectral data previously reported. 7-hydroxy-6-methoxycoumarin compound showed cytotoxic effect against P-388 murine leukemia cell with IC50 value of 16.5 mg/mL. 7-hydroxy-6-methoxycoumarin compound was reported for the first time from genus of Chisocheton.

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Published
2020-08-10
How to Cite
Rodrigo, M. (2020). Compounds 7-Hydroxy-6-Metoxic Cytotoxic Cytotoxic Stem Leather From Chisochetonmacrophyllus (Meliaceae) Bark. International Journal of Science and Society, 2(2), 363 - 367. https://doi.org/10.54783/ijsoc.v2i2.180